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American stock index futures maintained a downward trend, with S&P 500 E-MINI futures down 0.3%, Nasdaq futures down 0.6% and Dow Jones futures down 0.1%.Baiyang Pharmaceutical Group signed an agreement with Peking University Hospital. On December 12, Baiyang Pharmaceutical Group signed a cooperation agreement with Peking University No.1 Hospital, and obtained the exclusive right to patent, clinical development and registration, production and marketing of "targeted integrin small molecule inhibitor" in Peking University Hospital.European Central Bank President Lagarde: The government should focus on reforms that promote growth.

European Central Bank President Lagarde: Reiterating the European Central Bank policy statement.Analysis: Lagarde's speech increased the market's bet to cut interest rates by 50 basis points. In December, the European Central Bank lowered its economic forecast and inflation forecast. At the press conference, European Central Bank President Lagarde paid attention to the downside risks of economic growth, especially mentioning that trade friction may put pressure on economic growth, and also mentioned that they discussed cutting interest rates by 50 basis points. Therefore, the atmosphere of the whole meeting is biased towards doves. The market then increased its bet on a 50 basis point rate cut after January. Although the possibility of a sharp interest rate cut in January is stable at 30%, the possibility of a 50 basis point interest rate cut in March has increased from 30% before the meeting to 40%, and the possibility of a 50 basis point interest rate cut in April has increased from 0% to 5%.Australia plans to force technology giants to pay for news content. The Australian government announced a new tax plan on the 12th, which will force technology giants to pay for news content to Australian media companies, otherwise they will face the risk of being charged higher taxes. According to the Australian government's plan, all digital platforms with an annual income of more than A $250 million (about US$ 160 million) in Australia must reach a commercial agreement with Australian media organizations on the use of news content, otherwise they will face the risk of being charged higher taxes. (Xinhua News Agency)

Central Economic Work Conference: Strengthening Expectation Management and Promoting Policy Implementation and Expectation Guidance in Coordination. The Central Economic Work Conference was held in Beijing from December 11th to 12th. The meeting stressed that it is necessary to coordinate development and safety, do a good job in safety production, and effectively prevent and respond to social security incidents in a timely manner. Strengthen synergy, oppose departmentalism, and form a joint force for implementation. Strengthen the expected management, promote policy implementation and expected guidance in coordination, and enhance policy guidance and influence. At the same time, we should accurately grasp the situation of the world, the country, the party and the society, strengthen strategic planning, and formulate suggestions for the 10 th Five-Year Plan of the Central Committee. (Xinhua News Agency)World Meteorological Organization: The possibility of La Nina in the next three months is more than 50%. The latest forecast released by the World Meteorological Organization on the 11th shows that the possibility of La Nina in the next three months is more than 50%. It is expected that the intensity of La Nina will be weak and the duration will be short. According to the introduction of the World Meteorological Organization, the current El Niñ o/Southern Oscillation (ENSO) index is in a neutral state, which is neither El Niñ o nor La Nina. According to the forecast, from December 2024 to February 2025, the possibility of changing from the current neutral state to La Nina phenomenon is 55%. The forecast also shows that from February to April 2025, the possibility of returning to neutral state is 55%. (Xinhua News Agency)European Central Bank President Lagarde: The inflation problem has not yet been completed. European Central Bank President Lagarde said that the inflation problem has not yet been completed and the anti-inflation task has not yet ended, but inflation is moving towards the goal.